Thinking Out Loud
It is often said that "clinging" or "craving" is the source of all suffering, and that a cessation of clinging or craving will bring about a cessation of suffering. Unfortunately, this is often heard as a recommendation against involvement, and a suggestion that detachment will end suffering.

Well, and perhaps it will: so will death.

A more auspicious solution, however, might be to remain engaged in life, but to cease wishing it were different. Which I realize is another suggestion open to misinterpretation. I don't mean "don't struggle against bad stuff." What happens to you may be a god's choice, but what you do about it is yours. You can rail and complain and cling to your unhappiness, or you can accept what's happened and work from there. Clinging to what you wish had happened, or what you hope will happen, or who's to blame, or what your expectations were, prevents you from working with what is.

To accept reality is not to approve of it. You need not like what's happened, you only need to stop clinging to your dislike, which is based entirely in "might-have-been" and thus blocks you from the present moment. (For which, read: "...from your life.")